Man, did I want to give Dean a hug at the end of this last episode.

And the way he just kept saying, "Sammy, no! Sammy, no!"...and his "I could use some help please,"...
Other thoughts:
Mischa Collins does deadpan really well.

I loved that moment when Dean was on the phone with him and as soon as Dean turned around, Cas was in the room, standing right in front of him. That he was still talking into the phone as he said, "I'm going to hang up now," was priceless.

And his hamburger obsession?
Since that was the most receptive, accommodating coroner the boys have ever had, I was bummed when he died. (Is it strange I get attached to characters I know I'll never see again?

)
I was glad that Sam's hunger ended up being for demon blood, because it was almost as though the story just dropped off originally, when he said he no longer craved it at the beginning of the season. (Not that I didn't believe him. I did. But I thought that story line died a little too easy for me.) It gave his character an interesting dimension I think it's been lacking lately. And that the episode had to end with him in demon blood rehab (AKA: Bobby's Demon Cellar) was a nice element.
Famine was nice and creepy. Good casting choice.
I think the fact that Dean didn't desire anything speaks to the fact that he's at this place where inside himself, he feels that he doesn't have the choice. He wants to believe it, and to everyone else he says he does, but maybe the larger part of him feels that it's inevitable: that no matter what he does, what he tries, it's just not going to go his way this time. Can you blame him? Most things, most big things, don't go his way. He couldn't stop his dad from dying, he couldn't stop the hellhounds from coming after him and dragging him back to hell. He couldn't stop his parents from having him, he couldn't stop the apocalypse from starting. He couldn't kill the Yellow Eyed Demon.
Cupid was a nice diversion. I really thought it was him until I figured out it was Famine and thought...
Ah, okay...the Second Horseman. Got it. makes me wonder what they're going to do with the Third Horseman, how they'll represent him.
"And what's with the hugging?"
"That's their handshake."
"I don't like it."
"No one likes it."
And no more episodes until the end of March?!?!?!?!?!?
Dude...what the hell, Eric Kripke?!?!?!? What the hell?????